My research goal is to create “Smart Genetic Switches” that precisely ON and OFF the genetic and epigenetic factor(s) of interest. Harnessing the genetic information acquired by high-throughput technologies, we can gain artificial control over desired cell-type-specific genes using DNA-based epigenetic switches and achieve targeted reprogramming and differentiation. Advancing our synthetic strategy to construct tailor-made switches for therapeutically important genes associated with diseases lik
